| R | Player | Hometown | HR |
| 1. | Zimmerman, Ryan | Washington | 270 |
| 2. | Phillips, Brandon | Raleigh | 211 |
| 3. | Seager, Kyle* | Charlotte | 207 |
| 5. | Hamilton, Josh | Raleigh | 200 |
| 6. | Durham, Ray | Charlotte | 192 |
| 7. | Grace, Mark | Winston-Salem | 173 |
| 8. | Hart, Jim Ray | Hookerton | 170 |
| 9. | Slaughter, Enos | Roxboro | 169 |
| 10. | Nixon, Trot | Durham | 137 |
| 11. | Covington, Wes | Laurinburg | 131 |
| 12. | Myers, Wil* | Thomasville | 129 |
| 13. | Burgess, Smoky | Caroleen | 126 |
| 14. | Hall, Jimmie | Mount Holly | 121 |
| 15. | Lockman, Whitey | Lowell | 114 |
| 16. | Hinton, Chuck | Rocky Mount | 113 |
| 17. | Stubbs, Franklin | Laurinburg | 104 |
| 18. | Altman, George | Goldsboro | 101 |
| 19. | Roberts, Brian | Durham | 97 |
| 20. | Tracy, Chad | Charlotte | 86 |
| *Active player. Stats through 2020 season. |